Stem Cell and Cell Therapy
According to the definition of Wikipidia, stem cells are primal cells found in all multi-cellular organisms that retain the ability to renew themselves through cell division and can differentiate into a wide range of specialized cell types. In general, stem cells can indefinitely divide and replicate themselves, and can be functional tissues through differentiation under the right conditions and signals.
Stem cells with potency to various cells are categorized as embryonic stem cells from blastocysts, adult stem cells in adult tissues, and cord blood stem cells in the umbilical cord. Based on potency, their differentiation potential are described as Totipotent, Pluripotent, and Multipotent. Embryonic stem cells are totipotent. They give rise to the derivates of the three germ layers: endoderm, mesoderm, and ectoderm. On the other hand, adult stem cells as undifferentiated cells found throughout the body are pluripotent and multipotent. They are separated from umbilical cord, bone marrow, lipocyte for the purpose of therapy.
However, in order to accurately address potency, there are many factors to be overcome. One of the major difficulties for stem cell research and use is to develop a culture method to acquire a larger volume of stem cells. For the maximization of cell density and viability during the culture, the control of the culture environment is significant and includes such factors as the composition of media, growth factor, cytokine, and bioreactor. When we culture stem cells for the use of stem cell treatments, physical chemistry stimuli are important to increase cell viability and adaptability in a similar manner under in vivo conditions.
Although we culture the same stem cells, it comes up with the different results between suspension culture and anchorage dependent cell culture. Furthermore, the culture mode and bioreactor have to be optimized based on the purpose of the research and the intention of differentiation to the target. Therefore, Biotron’s policy is not only to provide the Bioreactor, Controller, Software, and Culture vessel to cover the variety of culture modes based on the customer’s needs, but also to supply the essential capability to perform accurate and effective stem cell research.
According to the definition of Wikipidia, stem cells are primal cells found in all multi-cellular organisms that retain the ability to renew themselves through cell division and can differentiate into a wide range of specialized cell types. In general, stem cells can indefinitely divide and replicate themselves, and can be functional tissues through differentiation under the right conditions and signals.
Stem cells with potency to various cells are categorized as embryonic stem cells from blastocysts, adult stem cells in adult tissues, and cord blood stem cells in the umbilical cord. Based on potency, their differentiation potential are described as Totipotent, Pluripotent, and Multipotent. Embryonic stem cells are totipotent. They give rise to the derivates of the three germ layers: endoderm, mesoderm, and ectoderm. On the other hand, adult stem cells as undifferentiated cells found throughout the body are pluripotent and multipotent. They are separated from umbilical cord, bone marrow, lipocyte for the purpose of therapy.
However, in order to accurately address potency, there are many factors to be overcome. One of the major difficulties for stem cell research and use is to develop a culture method to acquire a larger volume of stem cells. For the maximization of cell density and viability during the culture, the control of the culture environment is significant and includes such factors as the composition of media, growth factor, cytokine, and bioreactor. When we culture stem cells for the use of stem cell treatments, physical chemistry stimuli are important to increase cell viability and adaptability in a similar manner under in vivo conditions.
Although we culture the same stem cells, it comes up with the different results between suspension culture and anchorage dependent cell culture. Furthermore, the culture mode and bioreactor have to be optimized based on the purpose of the research and the intention of differentiation to the target. Therefore, Biotron’s policy is not only to provide the Bioreactor, Controller, Software, and Culture vessel to cover the variety of culture modes based on the customer’s needs, but also to supply the essential capability to perform accurate and effective stem cell research.
